Integrating Innovative Approaches for Competitive and Sustainable Performance across the Mediterranean Aquaculture Value Chain

Publications and Open Access Data



CORDIS Editorial Team and Moutou, K., 2023. Modernising the Mediterranean’s marine fish farming sector. CORDIS – Results in Brief.

Smith, P., Cortinovis, L., Pretto, T., Manfrin, A., Florio, D., Fioravanti, M., Baron, S., Le Devendec, L., Jouy, E., Le Breton, A. and Picon-Camacho, S., 2023. Setting epidemiological cut-off values for Vibrio harveyi relevant to MIC data generated by a standardised microdilution method. Diseases of Aquatic Organisms155, pp.35-42.

Smith, P., Le Devendec, L., Jouy, E., Larvor, E., Le Breton, A., Picon-Camacho, S., ana Zrnčić, S., Zupičić, I.G., Karataş, S., Verner-Jeffreys, D. and Joseph, A.W., 2023. Epidemiological cut-off values for Vibrio anguillarum MIC and disc diffusion data generated by standardised methods. Diseases of Aquatic Organisms155, pp.109-123.



Masi, M., Di Pasquale, J., Vecchio, Y., Pauselli, G., Tribilustova, E., & Adinolfi, F. (2022). A cross-sectional study in Mediterranean European countries to support stakeholders in addressing future market demands: Consumption of farmed fish products. Aquaculture Reports24, 101133. DOI: 10.1016/j.aqrep.2022.101133

Oikonomou, S., Kazlari, Z., Papapetrou, M., Papanna, K., Papaharisis, L., Manousaki, T., … & Chatziplis, D. (2022). Genome Wide Association (GWAS) Analysis and genomic heritability for parasite resistance and growth in European seabass. Aquaculture Reports24, 101178.

Errani, F., Volpe, E., Riera-Ferrer, E., Caffara, M., Padrós, F., Gustinelli, A., … & Ciulli, S. (2022). Development and diagnostic validation of a one-step multiplex RT-PCR assay as a rapid method to detect and identify Nervous Necrosis Virus (NNV) and its variants circulating in the Mediterranean. PloS one17(8), e0273802.

Valdivieso, A., Sánchez-Baizán, N., Mitrizakis, N., Papandroulakis, N., & Piferrer, F. (2022). Development of epigenetic biomarkers with diagnostic and prognostic value to assess the lasting effects of early temperature changes in farmed fish. Aquaculture, 738918.

Dominguez, D., Castro, P., Lall, S., Montero, D., Zamorano, M. J., Fontanillas, R., & Izquierdo, M. (2022). Effects of Menadione Sodium Bisulphite (Vitamin K3) Supplementation of the Diets Based on Plant Feed Ingredients on Growth and Bone Health of Gilthead Seabream (Sparus aurata) Fingerlings. Aquaculture Nutrition2022.

Padrós, F., Caggiano, M., Toffan, A., Constenla, M., Zarza, C., & Ciulli, S. (2022). Integrated Management Strategies for Viral Nervous Necrosis (VNN) Disease Control in Marine Fish Farming in the Mediterranean. Pathogens11(3), 330.

Pacorig, V., Galeotti, M., & Beraldo, P. (2022). Multiparametric Semi-quantitative Scoring System for the histological evaluation of marine fish larval and juvenile quality. Aquaculture Reports26, 101285.

Acosta, F., Bravo, J., Monzón-Atienza, L., Galindo-Villegas, J., Torecillas, S., & Montero, D. (2022). Peracetic acid can be used as a disinfectant for gilthead sea bream (Sparus aurata) juveniles without affecting fish welfare. Aquaculture Reports24, 101107.

Villanueva, B., Fernández, A., Peiró-Pastor, R., Peñaloza, C., Houston, R. D., Sonesson, A. K., … & Saura, M. (2022). Population structure and genetic variability in wild and farmed Mediterranean populations of gilthead seabream and European seabass inferred from a 60K combined species SNP array. Aquaculture Reports24, 101145.

Besson, M., Rombout, N., Salou, G., Vergnet, A., Cariou, S., Bruant, J. S., … & Vandeputte, M. (2022). Potential for genomic selection on feed efficiency in gilthead sea bream (Sparus aurata), based on individual feed conversion ratio, carcass and lipid traits. Aquaculture Reports24, 101132.

Najafpour, B., Pinto, P. I., Canario, A. V. M., & Power, D. M. (2022). Quantifying dominant bacterial genera detected in metagenomic data from fish eggs and larvae using genus‐specific primers. MicrobiologyOpen11(3), e1274.

Kourkouta, C., Tsipourlianos, A., Power, D. M., Moutou, K. A., & Koumoundouros, G. (2022). Variability of key-performance-indicators in commercial gilthead seabream hatcheries. Scientific Reports12(1), 1-13.


Fragkoulis, S., & Koumoundouros, G. (2021). Simple morphometrics for predicting lordosis-induced deviations of body-shape in reared Gilthead seabream (Sparus aurata L.). bioRxiv.

Zrnčić, S., Fioravanti, M. L., Gustinelli, A., Oraić, D., Zupičić, I. G., Pavlinec, Ž., … & Furones, D. (2021). Survey on laboratories and consultants working in the diagnostics of European seabass and gilthead seabream diseases: preliminary results. Bulletin of the European Association of Fish Pathologist41, 81-90.

Najafpour, B., Pinto, P. I., Moutou, K. A., Canario, A. V., & Power, D. M. (2021). Factors driving bacterial microbiota of eggs from commercial hatcheries of European seabass and gilthead seabream. Microorganisms9(11), 2275.

Li, L., Cardoso, J. C., Félix, R. C., Mateus, A. P., Canário, A. V., & Power, D. M. (2021). Fish lysozyme gene family evolution and divergent function in early development. Developmental & Comparative Immunology114, 103772.

Ferosekhan, S., Turkmen, S., Pérez-García, C., Xu, H., Gómez, A., Shamna, N., … & Kaushik, S. (2021). Influence of Genetic Selection for Growth and Broodstock Diet n-3 LC-PUFA Levels on Reproductive Performance of Gilthead Seabream, Sparus aurata. Animals11(2), 519.

Xu X., Ferosekhan S., Turkmen S., Afonso J.M., Zamorano M.J., Izquierdo, M. (2021). High broodstock fads2 expression combined with nutritional programing through broodstock diet improves the use of low fishmeal and low fish oil diets in gilthead seabream (Sparus aurata) progeny. Aquaculture 535, 736321. doi:

Naya-Català, F., Simó-Mirabet, P., Calduch-Giner, J., & Pérez-Sánchez, J. (2021). Transcriptomic profiling of Gh/Igf system reveals a prompted tissue-specific differentiation and novel hypoxia responsive genes in gilthead sea bream. Scientific Reports11(1), 1-13.

Acosta, F., Montero, D., Izquierdo, M., & Galindo-Villegas, J. (2021). High-level biocidal products effectively eradicate pathogenic γ-proteobacteria biofilms from aquaculture facilities. Aquaculture532, 736004.

Penaloza, C., Manousaki, T., Franch, R., Tsakogiannis, A., Sonesson, A. K., Aslam, M. L., … & Tsigenopoulos, C. S. (2021). Development and testing of a combined species SNP array for the European seabass (Dicentrarchus labrax) and gilthead seabream (Sparus aurata). Genomics113(4), 2096-2107.

Papapetrou, M., Kazlari, Z., Papanna, K., Papaharisis, L., Oikonomou, S., Manousaki, T., … & Chatziplis, D. (2021). On the trail of detecting genetic (co) variation between resistance to parasite infections (Diplectanum aequans and Lernanthropus kroyeri) and growth in European seabass (Dicentrarchus labrax). Aquaculture Reports20, 100767.

Dominguez, D., Montero, D., Zamorano, M. J., Castro, P., Fontanillas, R., Prabhu, P. A. J., & Izquierdo, M. (2021). Effects of vitamin D3 supplementation in gilthead seabream (Sparus aurata) juveniles fed diets high in plant based feedstuffs. Aquaculture543, 736991.

Kourkouta, C., Printzi, A., Geladakis, G., Mitrizakis, N., Papandroulakis, N., & Koumoundouros, G. (2021). Long lasting effects of early temperature exposure on the swimming performance and skeleton development of metamorphosing Gilthead seabream (Sparus aurata L.) larvae. Scientific reports11(1), 1-11.

Fragkoulis, S., Kerasovitis, D., Batargias, C., & Koumoundouros, G. (2021). Body-shape trajectories and their genetic variance component in Gilthead seabream (Sparus aurata L.). Scientific reports11(1), 1-10.

Lorenzo Felipe, A., Shin, H. S., León-Bernabeu, S., Pérez García, C., Zamorano Serrano, M. J., Pérez-Sánchez, J., & Afonso López, J. M. (2021). The Effect of the Deformity Genetic Background of the Breeders on the Spawning Quality of Gilthead Seabream (Sparus aurata L.). Frontiers in Marine Science.

Carvalho, M., Montero, D., Torrecillas, S., Castro, P., Zamorano, M. J., & Izquierdo, M. (2021). Hepatic biochemical, morphological and molecular effects of feeding microalgae and poultry oils to gilthead sea bream (Sparus aurata). Aquaculture532, 736073.

Carvalho, M., Montero, D., Domenici, P., Afonso, J. M., & Izquierdo, M. (2021). Dietary novel oils modulate neural function and preserve locomotor response in gilthead sea bream (Sparus aurata) juveniles by regulating synthesis and contents of fatty acids in brain. Aquaculture, 737873.

Peruzza, L., Pascoli, F., Dalla Rovere, G., Franch, R., Ferraresso, S., Babbucci, M., … & Bargelloni, L. (2021). Transcriptome analysis reveals a complex response to the RGNNV/SJNNV reassortant Nervous Necrosis Virus strain in sea bream larvae. Fish & Shellfish Immunology114, 282-292.


Dominguez, D., Sehnine, Z., Castro, P., Zamorano, M. J., Robaina, L., Fontanillas, R., … & Izquierdo, M. (2020). Dietary manganese levels for gilthead sea bream (Sparus aurata) fingerlings fed diets high in plant ingredients. Aquaculture529, 735614.

Carvalho, M., Montero, D., Rosenlund, G., Fontanillas, R., Ginés, R., & Izquierdo, M. (2020). Effective complete replacement of fish oil by combining poultry and microalgae oils in practical diets for gilthead sea bream (Sparus aurata) fingerlings. Aquaculture529, 735696.

Zrnčić, S., Padrós, F., Mladineo, I., Fioravanti, M. L., Gustinelli, A., Palenzuela, O., … & Brun, E. (2020). Bottlenecks in diagnostics of Mediterranean fish diseases. Bulletin of the European Association of Fish Pathologists.

Rigos G., Kogiannou D., Padrós F., Cristòfol C., Florio D., Fioravanti M.L, Zarza C. (2020). Best therapeutic practices for the use of antibacterial agents in finfish aquaculture: a particular view on European seabass (Dicentrarchus labrax) and gilthead seabream (Sparus aurata) in Mediterranean aquaculture. Reviews in Aquaculure, 1-39. doi:

Palstra A.P., Roque A., Kruijt L., Jehannet P., Pérez-Sánchez J., Dirks R.P. (2020). Pysiological Effects of Water Flow Induced Swimming Exercise in Seabream Sparus aurata. Frontiers in Physiology 11:610049. doi:

Najafpour B, Cardoso JCR, Canario AVM and Power DM (2020). Specific Evolution and Gene Family Expansion of Complement 3 and Regulatory Factor H in Fish. Front. Immunol. 11:568631. doi: 10.3389/fimmu.2020.568631

Simó-Mirabet P., Perera E., Calduch-Giner J.A., Pérez-Sánchez J. (2020) Local DNA methylation helps to regulate muscle sirtuin 1 gene expression across season and advancing age in gilthead sea bream (Sparus aurata). Frontiers in Zoology 17:15. doi:

Lama R., Pereiro P., Valenzuela-Muñoz V., Gallardo-Escárate C., Tort L., Figueras A., Novoa B. (2020) RNA-Seq analysis of European sea bass (Dicentrarchus labrax L.) infected with nodavirus reveals powerful modulation of the stress response. Veterinary Research 51:64. doi:

Volpe E., Gustinelli A., Caffaraa M., Errani F., Quaglio F., Fioravanti M.L., Ciulli S. (2020) Viral nervous necrosis outbreaks caused by the RGNNV/SJNNV reassortant betanodavirus in gilthead sea bream (Sparus aurata) and European sea bass (Dicentrarchus labrax). Aquaculture 523:735155. doi:

Perera E, Rosell-Moll E, Naya-Català F, Simó-Mirabet P, Calduch-Giner J, Pérez-Sánchez J. Effects of genetics and early-life mild hypoxia on size variation in farmed gilthead sea bream (Sparus aurata). Fish Physiology and Biochemistry. doi: 10.1007/s10695-020-00899-1. Full text available here.

Turkmen, S., Zamorano, M. J., Xu, H., Fernández-Palacios, H., Robaina, L., Kaushik, S., & Izquierdo, M. (2020). Parental LC-PUFA biosynthesis capacity and nutritional intervention with alpha-linolenic acid affect performance of Sparus aurata progeny. Journal of Experimental Biology223(23), jeb214999.

Ferosekhan, S., Xu, H., Turkmen, S., Gómez, A., Afonso, J. M., Fontanillas, R., … & Izquierdo, M. (2020). Reproductive performance of gilthead seabream (Sparus aurata) broodstock showing different expression of fatty acyl desaturase 2 and fed two dietary fatty acid profiles. Scientific reports10(1), 1-14.

Xu, H., Ferosekhan, S., Turkmen, S., Afonso, J. M., Zamorano, M. J., & Izquierdo, M. (2020). Influence of parental fatty acid desaturase 2 (Fads2) expression and diet on gilthead seabream (sparus aurata) offspring fads2 expression during ontogenesis. Animals10(11), 2191.

Ferosekhan, S., Turkmen, S., Xu, H., Afonso, J. M., Zamorano, M. J., Kaushik, S., & Izquierdo, M. (2020). The relationship between the expression of fatty acyl desaturase 2 (Fads2) gene in peripheral blood cells (pbcs) and liver in gilthead seabream, sparus aurata broodstock fed a low n-3 lc-pufa diet. Life10(7), 117.

Pereiro, P., Lama, R., Moreira, R., Valenzuela-Muñoz, V., Gallardo-Escárate, C., Novoa, B., & Figueras, A. (2020). Potential involvement of lncRNAs in the modulation of the transcriptome response to nodavirus challenge in European sea bass (Dicentrarchus labrax L.). Biology9(7), 165.


Lama R., Pereiro P., Novoa B., Coll J. (2019) Sea Bass Immunization to Downsize the Betanodavirus Protein Displayed in the Surface of Inactivated Repair-Less Bacteria. Vaccines 7:94. doi: 10.3390/vaccines7030094

Domínguez, D., Sarmiento, P., Sehnine, Z., Castro, P., Robaina, L., Fontanillas, R., Prabhu, P.A.J., Izquierdo, M. (2019) Effects of copper levels in diets high in plant ingredients on gilthead sea bream (Sparus aurata) fingerlings. Aquaculture 507, pp. 466-474. doi: 10.1016/j.aquaculture.2019.04.044

Turkmen S, Perera E, Zamorano MJ, Simó-Mirabet P, Xu H, Pérez-Sánchez J, Izquierdo M. (2019) Effects of dietary lipid composition and fatty acid desaturase 2 expression in broodstock gilthead sea bream on lipid metabolism-related genes and methylation of the fads2 gene promoter in their offspring. International Journal of Molecular Sciences 20: 6250. doi:

Perera E, Turkmen S, Simó-Mirabet P, Zamorano MJ, Xu H, Naya-Català F, Izquierdo M, Pérez-Sánchez J. (2019) Stearoyl-CoA desaturase (scd1a) is epigenetically regulated by broodstock nutrition in gilthead sea bream (Sparus aurata). Epigenetics Volume 10:11. doi: Click here to access the full text.

Stefanos Fragkoulis, Alice Printzi, George Geladakis, Nikos Katribouzas & George Koumoundouros (2019). Recovery of haemal lordosis in Gilthead seabream (Sparus aurata L.). Scientific Reports volume 9, Article number: 9832. doi:

Kazazić SP, Topić Popović N, StrunjakPerović I, Babić S, Florio D, Fioravanti M, et al. (2019). Matrix-assisted laser desorption/ionization time of flight mass spectrometry identification of Vibrio (Listonella) anguillarum isolated from sea bass and sea bream. PLoS ONE 14(11): e0225343. doi:

Snježana Pečur Kazazić, Natalija Topić Popović, Ivančica Strunjak-Perović, Daniela Florio, Maria Fioravanti, Sanja Babić, Rozelindra Čož-Rakovac (2019). Fish photobacteriosis – The importance of rapid and accurate identification of Photobacterium damselae subsp. piscicida. Journal of Fish Diseases 42/8: 2101-1209. doi: 10.1111/jfd.13022. Click here to access the full text.

M. Vandeputte, P.‐A. Gagnaire, F. Allal (2019). The European sea bass: a key marine fish model in the wild and in aquaculture.  Animal Genetics 50/3:195-206. doi: 10.1111/age.12779. Click here to access the full text.

Domínguez, D., Sehnine, Z., Castro, P., Robaina, L., Fontanillas, R., Prabhu, P.A.J., Izquierdo, M. (2019) Optimum selenium levels in diets high in plant-based feedstuffs for gilthead sea bream (Sparus aurata) fingerlings. Aquaculture Nutrition 26(2), pp. 579-589. doi: 10.1111/anu.13019


Simó-Mirabet P, Erick Perera E, Calduch-Giner JA,  Afonso JM, Pérez-Sánchez J. (2018) Co-expression Analysis of Sirtuins and Related Metabolic Biomarkers in Juveniles of Gilthead Sea Bream (Sparus aurata) With Differences in Growth Performance. Frontiers in Physiology. Volume 9, article 608. doi: 10.3389/fphys.2018.00608

Pérez-Sánchez J, Simó-Mirabet P, Naya F, Martos-Sitcha JA, Perera E, Bermejo-Nogales A, Benedito-Palos L, Calduch-Giner JA (2018). Somatotropic Axis Regulation Unravels the Differential Effects of Nutritional and Environmental Factors in Growth Performance of Marine Farmed Fishes. Frontiers in Endocrinology. doi: 10.3389/fendo.2018.00687


Open Access Data

All Open Access Data generated within PerformFISH can be found in the PerformFISH Community in Zenodo

Page updated: October 2, 2023