Integrating Innovative Approaches for Competitive and Sustainable Performance across the Mediterranean Aquaculture Value Chain

Publications and Open Access Data



Xu X., Ferosekhan S., Turkmen S., Afonso J.M., Zamorano M.J., Izquierdo, M. (2021). High broodstock fads2 expression combined with nutritional programing through broodstock diet improves the use of low fishmeal and low fish oil diets in gilthead seabream (Sparus aurata) progeny. Aquaculture 535, 736321. doi:

Naya-Català, F., Simó-Mirabet, P., Calduch-Giner, J., & Pérez-Sánchez, J. (2021). Transcriptomic profiling of Gh/Igf system reveals a prompted tissue-specific differentiation and novel hypoxia responsive genes in gilthead sea bream. Scientific Reports11(1), 1-13.

Acosta, F., Montero, D., Izquierdo, M., & Galindo-Villegas, J. (2021). High-level biocidal products effectively eradicate pathogenic γ-proteobacteria biofilms from aquaculture facilities. Aquaculture532, 736004.

Penaloza, C., Manousaki, T., Franch, R., Tsakogiannis, A., Sonesson, A. K., Aslam, M. L., … & Tsigenopoulos, C. S. (2021). Development and testing of a combined species SNP array for the European seabass (Dicentrarchus labrax) and gilthead seabream (Sparus aurata). Genomics113(4), 2096-2107.

Papapetrou, M., Kazlari, Z., Papanna, K., Papaharisis, L., Oikonomou, S., Manousaki, T., … & Chatziplis, D. (2021). On the trail of detecting genetic (co) variation between resistance to parasite infections (Diplectanum aequans and Lernanthropus kroyeri) and growth in European seabass (Dicentrarchus labrax). Aquaculture Reports20, 100767.

Dominguez, D., Montero, D., Zamorano, M. J., Castro, P., Fontanillas, R., Prabhu, P. A. J., & Izquierdo, M. (2021). Effects of vitamin D3 supplementation in gilthead seabream (Sparus aurata) juveniles fed diets high in plant based feedstuffs. Aquaculture543, 736991.

Kourkouta, C., Printzi, A., Geladakis, G., Mitrizakis, N., Papandroulakis, N., & Koumoundouros, G. (2021). Long lasting effects of early temperature exposure on the swimming performance and skeleton development of metamorphosing Gilthead seabream (Sparus aurata L.) larvae. Scientific reports11(1), 1-11.

Fragkoulis, S., Kerasovitis, D., Batargias, C., & Koumoundouros, G. (2021). Body-shape trajectories and their genetic variance component in Gilthead seabream (Sparus aurata L.). Scientific reports11(1), 1-10.

Lorenzo Felipe, A., Shin, H. S., León-Bernabeu, S., Pérez García, C., Zamorano Serrano, M. J., Pérez-Sánchez, J., & Afonso López, J. M. (2021). The Effect of the Deformity Genetic Background of the Breeders on the Spawning Quality of Gilthead Seabream (Sparus aurata L.). Frontiers in Marine Science.

Carvalho, M., Montero, D., Torrecillas, S., Castro, P., Zamorano, M. J., & Izquierdo, M. (2021). Hepatic biochemical, morphological and molecular effects of feeding microalgae and poultry oils to gilthead sea bream (Sparus aurata). Aquaculture532, 736073.

Carvalho, M., Montero, D., Domenici, P., Afonso, J. M., & Izquierdo, M. (2021). Dietary novel oils modulate neural function and preserve locomotor response in gilthead sea bream (Sparus aurata) juveniles by regulating synthesis and contents of fatty acids in brain. Aquaculture, 737873.

Peruzza, L., Pascoli, F., Dalla Rovere, G., Franch, R., Ferraresso, S., Babbucci, M., … & Bargelloni, L. (2021). Transcriptome analysis reveals a complex response to the RGNNV/SJNNV reassortant Nervous Necrosis Virus strain in sea bream larvae. Fish & Shellfish Immunology114, 282-292.


Rigos G., Kogiannou D., Padrós F., Cristòfol C., Florio D., Fioravanti M.L, Zarza C. (2020). Best therapeutic practices for the use of antibacterial agents in finfish aquaculture: a particular view on European seabass (Dicentrarchus labrax) and gilthead seabream (Sparus aurata) in Mediterranean aquaculture. Reviews in Aquaculure, 1-39. doi:

Palstra A.P., Roque A., Kruijt L., Jehannet P., Pérez-Sánchez J., Dirks R.P. (2020). Pysiological Effects of Water Flow Induced Swimming Exercise in Seabream Sparus aurata. Frontiers in Physiology 11:610049. doi:

Najafpour B, Cardoso JCR, Canario AVM and Power DM (2020). Specific Evolution and Gene Family Expansion of Complement 3 and Regulatory Factor H in Fish. Front. Immunol. 11:568631. doi: 10.3389/fimmu.2020.568631

Simó-Mirabet P., Perera E., Calduch-Giner J.A., Pérez-Sánchez J. (2020) Local DNA methylation helps to regulate muscle sirtuin 1 gene expression across season and advancing age in gilthead sea bream (Sparus aurata). Frontiers in Zoology 17:15. doi:

Lama R., Pereiro P., Valenzuela-Muñoz V., Gallardo-Escárate C., Tort L., Figueras A., Novoa B. (2020) RNA-Seq analysis of European sea bass (Dicentrarchus labrax L.) infected with nodavirus reveals powerful modulation of the stress response. Veterinary Research 51:64. doi:

Volpe E., Gustinelli A., Caffaraa M., Errani F., Quaglio F., Fioravanti M.L., Ciulli S. (2020) Viral nervous necrosis outbreaks caused by the RGNNV/SJNNV reassortant betanodavirus in gilthead sea bream (Sparus aurata) and European sea bass (Dicentrarchus labrax). Aquaculture 523:735155. doi:

Perera E, Rosell-Moll E, Naya-Català F, Simó-Mirabet P, Calduch-Giner J, Pérez-Sánchez J. Effects of genetics and early-life mild hypoxia on size variation in farmed gilthead sea bream (Sparus aurata). Fish Physiology and Biochemistry. doi: 10.1007/s10695-020-00899-1. Full text available here.

Turkmen, S., Zamorano, M. J., Xu, H., Fernández-Palacios, H., Robaina, L., Kaushik, S., & Izquierdo, M. (2020). Parental LC-PUFA biosynthesis capacity and nutritional intervention with alpha-linolenic acid affect performance of Sparus aurata progeny. Journal of Experimental Biology223(23), jeb214999.

Ferosekhan, S., Xu, H., Turkmen, S., Gómez, A., Afonso, J. M., Fontanillas, R., … & Izquierdo, M. (2020). Reproductive performance of gilthead seabream (Sparus aurata) broodstock showing different expression of fatty acyl desaturase 2 and fed two dietary fatty acid profiles. Scientific reports10(1), 1-14.

Xu, H., Ferosekhan, S., Turkmen, S., Afonso, J. M., Zamorano, M. J., & Izquierdo, M. (2020). Influence of parental fatty acid desaturase 2 (Fads2) expression and diet on gilthead seabream (sparus aurata) offspring fads2 expression during ontogenesis. Animals10(11), 2191.

Ferosekhan, S., Turkmen, S., Xu, H., Afonso, J. M., Zamorano, M. J., Kaushik, S., & Izquierdo, M. (2020). The relationship between the expression of fatty acyl desaturase 2 (Fads2) gene in peripheral blood cells (pbcs) and liver in gilthead seabream, sparus aurata broodstock fed a low n-3 lc-pufa diet. Life10(7), 117.

Pereiro, P., Lama, R., Moreira, R., Valenzuela-Muñoz, V., Gallardo-Escárate, C., Novoa, B., & Figueras, A. (2020). Potential involvement of lncRNAs in the modulation of the transcriptome response to nodavirus challenge in European sea bass (Dicentrarchus labrax L.). Biology9(7), 165.


Lama R., Pereiro P., Novoa B., Coll J. (2019) Sea Bass Immunization to Downsize the Betanodavirus Protein Displayed in the Surface of Inactivated Repair-Less Bacteria. Vaccines 7:94. doi: 10.3390/vaccines7030094

Domínguez, D., Sarmiento, P., Sehnine, Z., Castro, P., Robaina, L., Fontanillas, R., Prabhu, P.A.J., Izquierdo, M. (2019) Effects of copper levels in diets high in plant ingredients on gilthead sea bream (Sparus aurata) fingerlings. Aquaculture 507, pp. 466-474. doi: 10.1016/j.aquaculture.2019.04.044

Turkmen S, Perera E, Zamorano MJ, Simó-Mirabet P, Xu H, Pérez-Sánchez J, Izquierdo M. (2019) Effects of dietary lipid composition and fatty acid desaturase 2 expression in broodstock gilthead sea bream on lipid metabolism-related genes and methylation of the fads2 gene promoter in their offspring. International Journal of Molecular Sciences 20: 6250. doi:

Perera E, Turkmen S, Simó-Mirabet P, Zamorano MJ, Xu H, Naya-Català F, Izquierdo M, Pérez-Sánchez J. (2019) Stearoyl-CoA desaturase (scd1a) is epigenetically regulated by broodstock nutrition in gilthead sea bream (Sparus aurata). Epigenetics Volume 10:11. doi: Click here to access the full text.

Stefanos Fragkoulis, Alice Printzi, George Geladakis, Nikos Katribouzas & George Koumoundouros (2019). Recovery of haemal lordosis in Gilthead seabream (Sparus aurata L.). Scientific Reports volume 9, Article number: 9832. doi:

Kazazić SP, Topić Popović N, StrunjakPerović I, Babić S, Florio D, Fioravanti M, et al. (2019). Matrix-assisted laser desorption/ionization time of flight mass spectrometry identification of Vibrio (Listonella) anguillarum isolated from sea bass and sea bream. PLoS ONE 14(11): e0225343. doi:

Snježana Pečur Kazazić, Natalija Topić Popović, Ivančica Strunjak-Perović, Daniela Florio, Maria Fioravanti, Sanja Babić, Rozelindra Čož-Rakovac (2019). Fish photobacteriosis – The importance of rapid and accurate identification of Photobacterium damselae subsp. piscicida. Journal of Fish Diseases 42/8: 2101-1209. doi: 10.1111/jfd.13022. Click here to access the full text.

M. Vandeputte, P.‐A. Gagnaire, F. Allal (2019). The European sea bass: a key marine fish model in the wild and in aquaculture.  Animal Genetics 50/3:195-206. doi: 10.1111/age.12779. Click here to access the full text.

Domínguez, D., Sehnine, Z., Castro, P., Robaina, L., Fontanillas, R., Prabhu, P.A.J., Izquierdo, M. (2019) Optimum selenium levels in diets high in plant-based feedstuffs for gilthead sea bream (Sparus aurata) fingerlings. Aquaculture Nutrition 26(2), pp. 579-589. doi: 10.1111/anu.13019


Simó-Mirabet P, Erick Perera E, Calduch-Giner JA,  Afonso JM, Pérez-Sánchez J. (2018) Co-expression Analysis of Sirtuins and Related Metabolic Biomarkers in Juveniles of Gilthead Sea Bream (Sparus aurata) With Differences in Growth Performance. Frontiers in Physiology. Volume 9, article 608. doi: 10.3389/fphys.2018.00608

Pérez-Sánchez J, Simó-Mirabet P, Naya F, Martos-Sitcha JA, Perera E, Bermejo-Nogales A, Benedito-Palos L, Calduch-Giner JA (2018). Somatotropic Axis Regulation Unravels the Differential Effects of Nutritional and Environmental Factors in Growth Performance of Marine Farmed Fishes. Frontiers in Endocrinology. doi: 10.3389/fendo.2018.00687


Open Access Data

All Open Access Data generated within PerformFISH can be found in the PerformFISH Community in Zenodo

Page updated: February 3, 2022